Magtrace®

A simple solution for breast cancer staging

Iron oxide. Sugar. Salt. Water. Four simple ingredients that together provide a safe and flexible way to stage early breast cancer, without compromising on clinical effectiveness1.

Particles optimized for nodes

The tiny particles are optimized for migration and uptake in the lymph nodes, providing a clear signal as well as visual guidance when performing sentinel node biopsy procedures.2

Everything you need. Any time you need it.

Magtrace® is a single injection, dual-tracer that allows you to plan injections weeks ahead of surgery2, to suit the schedules and your patients without compromising on efficacy or accuracy1.

Put patient comfort first

Eliminate patient pain by injecting the Magtrace® lymphatic tracer intra-operatively after anesthesia for mastectomy. If injected pre-operatively, it has been noted to cause minimal patient discomfort3.

No benefit? No surgery. No brainer.

The SentiNOT study2 demonstrated that up to 80% of high-risk DCIS patients can may be able to avoid unnecessary lymph node surgery with the Magtrace® lymphatic tracer and the 'Delayed' SLNB approach.

With its long-term detection window, physicians may not need to proceed with axillary surgery once pathology confirms there is no benefit.

Particles optimized for nodes

The tiny particles are optimized for migration and uptake in the lymph nodes, providing a clear signal as well as visual guidance when performing sentinel node biopsy procedures.2

Everything you need. Any time you need it.

Magtrace® is a single injection, dual-tracer that allows you to plan injections weeks ahead of surgery2, to suit the schedules and your patients without compromising on efficacy or accuracy1.

Put patient comfort first

Eliminate patient pain by injecting the Magtrace® lymphatic tracer intra-operatively after anesthesia for mastectomy. If injected pre-operatively, it has been noted to cause minimal patient discomfort3.

No benefit? No surgery. No brainer.

The SentiNOT study2 demonstrated that up to 80% of high-risk DCIS patients can may be able to avoid unnecessary lymph node surgery with the Magtrace® lymphatic tracer and the 'Delayed' SLNB approach.

With its long-term detection window, physicians may not need to proceed with axillary surgery once pathology confirms there is no benefit.

Seed plus tracer, working in harmony

Magtrace® lymphatic tracer can be paired with the Magseed Pro® marker to perform tissue localization and axillary staging together, using just one probe3.

Why magnetic tracers?

Magnetic tracers have been designed to simplify breast cancer staging, to make it more convenient, more widely available and never compromising on clinical effectiveness.

  • Accurate

    Clinical trials have shown Magtrace® to be non-inferior to the combination of radioisotope +/- blue dyes1.

  • Safe

    No reported allergic reactions or anaphylaxis in over 200,000 cases 4.

  • Flexible

    The Magtrace® lymphatic tracer allows you to plan injections weeks ahead of surgery2

  • Radiation-free

    Iron oxide. Sugar. Salt. Water. A simple solution to replace radioactive tracers.

Trusted by experts, demanded by patients

Hear how world-leading physicians are enjoying the truly unique benefits of the Magtrace® lymphatic tracer to provide a more flexible approach to SLNB and avoid surgery when it’s not needed.1

Dr. Ashley Simpson
Dr. Anne Peled
Dr. Janette Gomez
Dr. Patricia Clark & Dr. Cindy Mak
Dr. Ashley Simpson
Dr. Anne Peled
Dr. Janette Gomez
Dr. Patricia Clark & Dr. Cindy Mak
Magtrace is a real game-changer to the way we treat breast cancer in the United States.
Dr. Laura Esserman UCSF Breast Care Center
It's life changing for the patient and practice changing for us. It does a great job.
Dr. Lucy De La Cruz MedStar Georgetown University Hospital
Given enough time and dispersement of this information and technology, Delayed Sentinel Node Biopsy will become a standard.
Dr. Shawna Willey Inova Schar Cancer Institute
This is the one product I've seen that provides a real benefit to the patient that is substantial.
Dr. Janette Gomez Allegheny General Hospital
Magtrace is a real game-changer to the way we treat breast cancer in the United States.
Dr. Laura Esserman UCSF Breast Care Center
It's life changing for the patient and practice changing for us. It does a great job.
Dr. Lucy De La Cruz MedStar Georgetown University Hospital
Given enough time and dispersement of this information and technology, Delayed Sentinel Node Biopsy will become a standard.
Dr. Shawna Willey Inova Schar Cancer Institute
This is the one product I've seen that provides a real benefit to the patient that is substantial.
Dr. Janette Gomez Allegheny General Hospital
Magtrace Collaboration
Dr. Kristalyn Gallagher
Holly Miller & Dr. Shawna Willey
Dr. Kelly Hewitt
Magtrace Collaboration
Dr. Kristalyn Gallagher
Holly Miller & Dr. Shawna Willey
Dr. Kelly Hewitt

Backed by data

200,000+

total patients treated5

98.7%

sentinel lymph node detection rate 1

2.4

average nodes obtained per patient5

Related Products

  1. 1 Pantiora et al (2022) Evolution and refinement of magnetically guided sentinel lymph node detection in breast cancer: meta-analysis. Br J Surg. 2023 Mar 30;110(4):410-419. doi: 10.1093/bjs/znac426 (Featuring 20 comparative studies for the Magseed® marker and guidewires)
  2. 2 Karakatsanis et al (2023) Delayed Sentinel Lymph Node Dissection in Patients with a Preoperative Diagnosis of Ductal Cancer In Situ by Preoperative Injection with Superparamagnetic Iron Oxide (SPIO) Nanoparticles: The SentiNot Study. Ann Surg Oncol. 2023 Jul;30(7):4064-4072. doi: 10.1245/s10434-022-13064-0 (Study featuring 254 patients from 6 hospitals)
  3. 3 Pantiora et al (2023) Magnetic Seed vs Guidewire Breast Cancer Localization With Magnetic Lymph Node Detection: A Randomized Clinical Trial. JAMA Surg. 2024 Mar 1;159(3):239-246. doi:10.1001/jamasurg
  4. 4 Data on file at Endomag. Data correct as of November 2025.
  5. 5 Data on file at Endomag. Data correct as of March 2025. (Internal Meta-Analysis 090724 of Clinical Studies).

Get started with your Magtrace® trial

Give your patients a better standard of breast cancer surgery without the need for radioactivity. Set up a Magtrace® lymphatic tracer evaluation today.

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  • 185,000+ patients already treated
  • Now sold through Hologic in the US & Canada
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